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Difference between revisions of "IMNM"

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               <li> <a href="investigators#jp" > Jack Parent, M.D.     </a> </li>
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               <li> <a href="investigators#jp" > Jack Parent, M.D. (Contact PI) </a> </li>
 
               <li> <a href="investigators#lli" > Lori L. Isom, Ph.D.    </a> </li>
 
               <li> <a href="investigators#lli" > Lori L. Isom, Ph.D.    </a> </li>
 
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     </ul>

Revision as of 11:25, 13 November 2014


iPSC and Mouse Neurocardiac Models (NS090364)


Specific Aims and Tasks

Utilize iPSC-derived cardiac myocytes and autonomic neurons as well as mouse models to determine whether heart rhythm disturbances are a cause of SUDEP in Dravet Syndrome, a severe childhood epilepsy with a high risk of SUDEP
  • Focus on SCN1A and SCN1B mutations and investigation of their effect on cardiac and autonomic neuron excitability

Principal Investigators



Citations



Protocols and Manuals



Publication Links



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